With the support of a one year pilot grant from NETRF, Tim Meyer established a collaborative group at UCL to study the immune microenvironment of NETs and the influence of therapy with a view to developing a rationale for immunotherapy. The project has been co-ordinated by a post-doctoral scantiest Clare Vesely, and unique expertise was provided by Sergio Quesada and Teresa Marafioti. The pilot data generated was so compelling that the NETRF have granted a further two years funding and this will allow the team to generate a comprehensive picture of the immune landscape of mid-gut and pancreatic NET. In the meantime, the first trials of immunotherapy for NET are underway and we await the initial results with interest.
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